As Latin American women continue to lead in politics, science, and entrepreneurship, they face a quieter but growing threat: dengue. In 2024 alone, the region saw over 13 million dengue cases, with new research revealing that women, especially those of reproductive age, are more likely to suffer severe complications. From biological factors like estrogen’s impact on immunity to social roles that increase mosquito exposure, the gender gap in arboviral infections is real and urgent. With evidence mounting from countries like Brazil, experts are calling for gender-sensitive public health strategies, including targeted vector control, reproductive care, and expanded vaccine access to protect those most at risk.